Pubblicazioni Recenti

  1. Adami G, Rossini M, Gatti D, Orsolini G, Idolazzi L, Viapiana O, Scarpa A and Canalis E. Hajdu Cheney Syndrome; report of a novel NOTCH2 mutation and treatment with denosumab. Bone. 2016;92:150-156.
  2. Amato E, Barbi S, Fassan M, Luchini C, Vicentini C, Brunelli M, Malleo G, Scarpa A and Malpeli G. RASSF1 tumor suppressor gene in pancreatic ductal adenocarcinoma: correlation of expression, chromosomal status and epigenetic changes. BMC Cancer. 2016;16:11.
  3. Andrea Ruzzenente1 FB, Marco Sandri BS2, Corrado Pedrazzani1, Matteo Brunelli3, Tommaso Campagnaro1, Simone Conci1, and Paola Capelli3 AG, Aldo Scarpa3 and Calogero Iacono1*. A Novel Prognostic Score based on Serum Alpha-Fetoprotein, Number of Nodules, and MYC Gene Status Predicts Prognosis of Patients after Liver Resection for Hepatocellular Carcinoma. J Integrative Oncology. 2016.
  4. Andrici J, Goeppert B, Sioson L, Clarkson A, Renner M, Stenzinger A, Tayao M, Watson N, Farzin M, Toon CW, Smith RC, Mittal A, Samra JS, Hugh TJ, Chou A, Lawlor RT, Weichert W, Schirmacher P, Sperandio N, Ruzzenente A, Scarpa A and Gill AJ. Loss of BAP1 Expression Occurs Frequently in Intrahepatic Cholangiocarcinoma. Medicine (Baltimore). 2016;95:e2491.
  5. ARC-Net Centre for Applied Research on Cancer Jeremy Jass Prize for Research Excellence in Pathology 2014. J Pathology. 2016;238:598.
  6. Azzariti A, Brunetti O, Porcelli L, Graziano G, Iacobazzi RM, Signorile M, Scarpa A, Lorusso V and Silvestris N. Potential predictive role of chemotherapy-induced changes of soluble CD40 ligand in untreated advanced pancreatic ductal adenocarcinoma. Onco Targets Ther. 2016;9:4681-6.
  7. Bailey P, Chang DK, Nones K, Johns AL, Patch AM, Gingras MC, Miller DK, Christ AN, Bruxner TJ, Quinn MC, Nourse C, Murtaugh LC, Harliwong I, Idrisoglu S, Manning S, Nourbakhsh E, Wani S, Fink L, Holmes O, Chin V, Anderson MJ, Kazakoff S, Leonard C, Newell F, Waddell N, Wood S, Xu Q, Wilson PJ, Cloonan N, Kassahn KS, Taylor D, Quek K, Robertson A, Pantano L, Mincarelli L, Sanchez LN, Evers L, Wu J, Pinese M, Cowley MJ, Jones MD, Colvin EK, Nagrial AM, Humphrey ES, Chantrill LA, Mawson A, Humphris J, Chou A, Pajic M, Scarlett CJ, Pinho AV, Giry-Laterriere M, Rooman I, Samra JS, Kench JG, Lovell JA, Merrett ND, Toon CW, Epari K, Nguyen NQ, Barbour A, Zeps N, Moran-Jones K, Jamieson NB, Graham JS, Duthie F, Oien K, Hair J, Grutzmann R, Maitra A, Iacobuzio-Donahue CA, Wolfgang CL, Morgan RA, Lawlor RT, Corbo V, Bassi C, Rusev B, Capelli P, Salvia R, Tortora G, Mukhopadhyay D, Petersen GM, Australian Pancreatic Cancer Genome I, Munzy DM, Fisher WE, Karim SA, Eshleman JR, Hruban RH, Pilarsky C, Morton JP, Sansom OJ, Scarpa A, Musgrove EA, Bailey UM, Hofmann O, Sutherland RL, Wheeler DA, Gill AJ, Gibbs RA, Pearson JV, Waddell N, Biankin AV and Grimmond SM. Genomic analyses identify molecular subtypes of pancreatic cancer. Nature. 2016;531:47-52.
  8. Botla SK, Savant S, Jandaghi P, Bauer AS, Mucke O, Moskalev EA, Neoptolemos JP, Costello E, Greenhalf W, Scarpa A, Gaida MM, Buchler MW, Strobel O, Hackert T, Giese NA, Augustin HG and Hoheisel JD. Early epigenetic down-regulation of microRNA-192 expression promotes pancreatic cancer progression. Cancer Res. 2016.
  9. Brandi J, Dalla Pozza E, Dando I, Biondani G, Robotti E, Jenkins R, Elliott V, Park K, Marengo E, Costello E, Scarpa A, Palmieri M and Cecconi D. Secretome protein signature of human pancreatic cancer stem-like cells. J Proteomics. 2016;136:1-12.
  10. Brandi J, Dando I, Pozza ED, Biondani G, Jenkins R, Elliott V, Park K, Fanelli G, Zolla L, Costello E, Scarpa A, Cecconi D and Palmieri M. Proteomic analysis of pancreatic cancer stem cells: Functional role of fatty acid synthesis and mevalonate pathways. J Proteomics. 2016.
  11. Bria E, Pilotto S, Simbolo M, Fassan M, de Manzoni G, Carbognin L, Sperduti I, Brunelli M, Cataldo I, Tomezzoli A, Mafficini A, Turri G, Karachaliou N, Rosell R, Tortora G and Scarpa A. Comprehensive molecular portrait using next generation sequencing of resected intestinal-type gastric cancer patients dichotomized according to prognosis. Sci Rep. 2016;6:22982.
  12. Caccese M, Ferrara R, Pilotto S, Carbognin L, Grizzi G, Calio A, Brunelli M, Cuppone F, Petraglia S, Scarpa A, Tortora G and Bria E. Current and developing therapies for the treatment of non-small cell lung cancer with ALK abnormalities: update and perspectives for clinical practice. Expert Opin Pharmacother. 2016.
  13. Carotenuto P, Fassan M, Pandolfo R, Lampis A, Vicentini C, Cascione L, Paulus-Hock V, Boulter L, Guest R, Quagliata L, Hahne JC, Ridgway R, Jamieson T, Athineos D, Veronese A, Visone R, Murgia C, Ferrari G, Guzzardo V, Evans TR, MacLeod M, Feng GJ, Dale T, Negrini M, Forbes SJ, Terracciano L, Scarpa A, Patel T, Valeri N, Workman P, Sansom O and Braconi C. Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers. Gut. 2016.
  14. Cordani M, Pacchiana R, Butera G, D’Orazi G, Scarpa A and Donadelli M. Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: involvement in cancer invasion and metastasis. Cancer Lett. 2016.
  15. Crippa S, Partelli S, Bassi C, Berardi R, Capelli P, Scarpa A, Zamboni G and Falconi M. Long-term outcomes and prognostic factors in neuroendocrine carcinomas of the pancreas: Morphology matters. Surgery. 2016;159:862-71.
  16. Del Re M, Tiseo M, Bordi P, D’Incecco A, Camerini A, Petrini I, Lucchesi M, Inno A, Spada D, Vasile E, Citi V, Malpeli G, Testa E, Gori S, Falcone A, Amoroso D, Chella A, Cappuzzo F, Ardizzoni A, Scarpa A and Danesi R. Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA. Oncotarget. 2016.
  17. Gingras MC, Covington KR, Chang DK, Donehower LA, Gill AJ, Ittmann MM, Creighton CJ, Johns AL, Shinbrot E, Dewal N, Fisher WE, Australian Pancreatic Cancer Genome I, Pilarsky C, Grutzmann R, Overman MJ, Jamieson NB, Van Buren G, 2nd, Drummond J, Walker K, Hampton OA, Xi L, Muzny DM, Doddapaneni H, Lee SL, Bellair M, Hu J, Han Y, Dinh HH, Dahdouli M, Samra JS, Bailey P, Waddell N, Pearson JV, Harliwong I, Wang H, Aust D, Oien KA, Hruban RH, Hodges SE, McElhany A, Saengboonmee C, Duthie FR, Grimmond SM, Biankin AV, Wheeler DA and Gibbs RA. Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation. Cell Rep. 2016;14:907-19.
  18. Jandaghi P, Najafabadi HS, Bauer AS, Papadakis AI, Fassan M, Hall A, Monast A, von Knebel Doeberitz M, Neoptolemos JP, Costello E, Greenhalf W, Scarpa A, Sipos B, Auld D, Lathrop M, Park M, Buchler MW, Strobel O, Hackert T, Giese NA, Zogopoulos G, Sangwan V, Huang S, Riazalhosseini Y and Hoheisel JD. Expression of DRD2 Is Increased in Human Pancreatic Ductal Adenocarcinoma and Inhibitors Slow Tumor Growth in Mice. Gastroenterology. 2016.
  19. Jeremy Jass Prize. Jeremy Jass Prize for Research Excellence in Pathology 2014. J Pathol. 2016;238:598.
  20. Khalil S, Fabbri E, Santangelo A, Bezzerri V, Cantu C, Di Gennaro G, Finotti A, Ghimenton C, Eccher A, Dechecchi M, Scarpa A, Hirshman B, Chen C, Ferracin M, Negrini M, Gambari R and Cabrini G. miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma. Oncotarget. 2016.
  21. Luchini C, Nottegar A, Pea A, Solmi M, Stubbs B, Capelli P, Sergi G, Manzato E, Fassan M, Wood LD, Scarpa A and Veronese N. Extra-nodal extension is an important prognostic parameter for both colonic and rectal cancer. Ann Oncol. 2016.
  22. Luchini C, Nottegar A, Pea A, Solmi M, Stubbs B, Capelli P, Sergi G, Manzato E, Fassan M, Wood LD, Scarpa A and Veronese N. Significance of the prognostic stratification of extranodal extension in colorectal cancer. Ann Oncol. 2016.
  23. Luchini C, Veronese N, Yachida S, Cheng L, Nottegar A, Stubbs B, Solmi M, Capelli P, Pea A, Barbareschi M, Fassan M, Wood LD and Scarpa A. Different Prognostic Roles Of Tumor Suppressor Gene BAP1 In Cancer: A Systematic Review With Meta-Analysis. Genes Chromosomes Cancer. 2016.
  24. Mafficini A, Amato E, Cataldo I, Rusev BC, Bertoncello L, Corbo V, Simbolo M, Luchini C, Fassan M, Cantu C, Salvia R, Marchegiani G, Tortora G, Lawlor RT, Bassi C and Scarpa A. Ampulla of Vater Carcinoma: Sequencing Analysis Identifies TP53 Status as a Novel Independent Prognostic Factor and Potentially Actionable ERBB, PI3K, and WNT Pathways Gene Mutations. Ann Surg. 2016.
  25. Mafficini A, Simbolo M, Parisi A, Rusev B, Luchini C, Cataldo I, Piazzola E, Sperandio N, Turri G, Franchi M, Tortora G, Bovo C, Lawlor RT and Scarpa A. BRCA somatic and germline mutation detection in paraffin embedded ovarian cancers by next-generation sequencing. Oncotarget. 2016;7:1076-83.
  26. Marchegiani G, Andrianello S, Malleo G, De Gregorio L, Scarpa A, Mino-Kenudson M, Maggino L, Ferrone CR, Lillemoe KD, Bassi C, Castillo CF and Salvia R. Does Size Matter in Pancreatic Cancer?: Reappraisal of Tumour Dimension as a Predictor of Outcome Beyond the TNM. Ann Surg. 2016.
  27. Marchegiani G, Andrianello S, Massignani M, Malleo G, Maggino L, Paiella S, Ferrone CR, Luchini C, Scarpa A, Capelli P, Mino-Kenudson M, Lillemoe KD, Bassi C, Castillo CF and Salvia R. Solid pseudopapillary tumors of the pancreas: Specific pathological features predict the likelihood of postoperative recurrence. J Surg Oncol. 2016;114:597-601.
  28. Nussbeck SY, Rabone M, Benson EE, Droege G, Mackenzie-Dodds J and Lawlor RT. ‘Life in Data’-Outcome of a Multi-Disciplinary, Interactive Biobanking Conference Session on Sample Data. Biopreserv Biobank. 2016.
  29. Pea A, Yu J, Rezaee N, Luchini C, He J, Dal Molin M, Griffin JF, Fedor H, Fesharakizadeh S, Salvia R, Weiss MJ, Bassi C, Cameron JL, Zheng L, Scarpa A, Hruban RH, Lennon AM, Goggins M, Wolfgang CL and Wood LD. Targeted DNA Sequencing Reveals Patterns of Local Progression in the Pancreatic Remnant Following Resection of Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas. Ann Surg. 2016.
  30. Pelosi G, Scarpa A, Forest F and Sonzogni A. The impact of immunohistochemistry on the classification of lung tumors. Expert Rev Respir Med. 2016.
  31. Peretti U, Ferrara R, Pilotto S, Kinspergher S, Caccese M, Santo A, Brunelli M, Calio A, Carbognin L, Sperduti I, Garassino M, Chilosi M, Scarpa A, Tortora G and Bria E. ALK gene copy number gains in non-small-cell lung cancer: prognostic impact and clinico-pathological correlations. Respir Res. 2016;17:105.
  32. Piro G, Carbone C, Cataldo I, Di Nicolantonio F, Giacopuzzi S, Aprile G, Simionato F, Boschi F, Zanotto M, Mina MM, Santoro R, Merz V, Sbarbati A, de Manzoni G, Scarpa A, Tortora G and Melisi D. An FGFR3 autocrine loop sustains acquired resistance to trastuzumab in gastric cancer patients. Clin Cancer Res. 2016.
  33. Ruzzenente A, Fassan M, Conci S, Simbolo M, Lawlor RT, Pedrazzani C, Capelli P, D’Onofrio M, Iacono C, Scarpa A and Guglielmi A. Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients. Ann Surg Oncol. 2016;23:1699-707.
  34. Silvestris N, Longo V, Cellini F, Reni M, Bittoni A, Cataldo I, Partelli S, Falconi M, Scarpa A, Brunetti O, Lorusso V, Santini D, Morganti A, Valentini V and Cascinu S. Neoadjuvant multimodal treatment of pancreatic ductal adenocarcinoma. Crit Rev Oncol Hematol. 2016;98:309-24.
  35. Simbolo M, Fassan M, Mafficini A, Lawlor RT, Ruzzenente A and Scarpa A. New genomic landscapes and therapeutic targets for biliary tract cancers. Front Biosci (Landmark Ed). 2016;21:707-18.
  36. Veronese N, Nottegar A, Pea A, Solmi M, Stubbs B, Capelli P, Sergi G, Manzato E, Fassan M, Wood LD, Scarpa A and Luchini C. Prognostic impact and implications of extracapsular lymph node involvement in colorectal cancer: a systematic review with meta-analysis. Ann Oncol. 2016;27:42-8.
  37. Yachida S, Wood LD, Suzuki M, Takai E, Totoki Y, Kato M, Luchini C, Arai Y, Nakamura H, Hama N, Elzawahry A, Hosoda F, Shirota T, Morimoto N, Hori K, Funazaki J, Tanaka H, Morizane C, Okusaka T, Nara S, Shimada K, Hiraoka N, Taniguchi H, Higuchi R, Oshima M, Okano K, Hirono S, Mizuma M, Arihiro K, Yamamoto M, Unno M, Yamaue H, Weiss MJ, Wolfgang CL, Furukawa T, Nakagama H, Vogelstein B, Kiyono T, Hruban RH and Shibata T. Genomic Sequencing Identifies ELF3 as a Driver of Ampullary Carcinoma. Cancer Cell. 2016;29:229-40.
  38. Zhang M, Wang Z, Obazee O, Jia J, Childs EJ, Hoskins J, Figlioli G, Mocci E, Collins I, Chung CC, Hautman C, Arslan AA, Beane-Freeman L, Bracci PM, Buring J, Duell EJ, Gallinger S, Giles GG, Goodman GE, Goodman PJ, Kamineni A, Kolonel LN, Kulke MH, Malats N, Olson SH, Sesso HD, Visvanathan K, White E, Zheng W, Abnet CC, Albanes D, Andreotti G, Brais L, Bueno-de-Mesquita HB, Basso D, Berndt SI, Boutron-Ruault MC, Bijlsma MF, Brenner H, Burdette L, Campa D, Caporaso NE, Capurso G, Cavestro GM, Cotterchio M, Costello E, Elena J, Boggi U, Gaziano JM, Gazouli M, Giovannucci EL, Goggins M, Gross M, Haiman CA, Hassan M, Helzlsouer KJ, Hu N, Hunter DJ, Iskierka-Jazdzewska E, Jenab M, Kaaks R, Key TJ, Khaw KT, Klein EA, Kogevinas M, Krogh V, Kupcinskas J, Kurtz RC, Landi MT, Landi S, Le Marchand L, Mambrini A, Mannisto S, Milne RL, Neale RE, Oberg AL, Panico S, Patel AV, Peeters PH, Peters U, Pezzilli R, Porta M, Purdue M, Quiros JR, Riboli E, Rothman N, Scarpa A, Scelo G, Shu XO, Silverman DT, Soucek P, Strobel O, Sund M, Malecka-Panas E, Taylor PR, Tavano F, Travis RC, Thornquist M, Tjonneland A, Tobias GS, Trichopoulos D, Vashist Y, Vodicka P, Wactawski-Wende J, Wentzensen N, Yu H, Yu K, Zeleniuch-Jacquotte A, Kooperberg C, Risch HA, Jacobs EJ, Li D, Fuchs C, Hoover R, Hartge P, Chanock SJ, Petersen GM, Stolzenberg-Solomon RS, Wolpin BM, Kraft P, Klein AP, Canzian F and Amundadottir LT. Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21. Oncotarget. 2016

In stampa

  1. Cocco P, Zucca M, Sanna S, Satta G, Angelucci E, Gabbas A, Monne M, Campagna M, Scarpa A and Ennas M. Interaction between dietary and lifestyle risk factors and N-acetyltransferase polymorphisms in B-cell lymphoma etiology. J Environ Anal Toxicol. in press.
  2. De Marchi G, Paiella S, Luchini C, Amodio A, Rusev B, Bassi C, Manfredi R and Frulloni L. A rare case of three different tumors in the same pancreatic specimen: a case report and brief review of the literature. J Gastrointest Oncol. in press.
  3. Humphris JL, Patch AM, Nones K, Bailey P, Johns AL, McKay S, Chang DK, Miller D, Marina Pajic M, Kassahn KS, Quinn MCJ, Bruxner TJC, Christ AN, Harliwong I, Idrisoglu S, Manning S, Nourse C, Nourbakhsh E, Stone A, Wilson PJ, M A, Fink JL, Holmes O, Kazakoff S, Leonard C, Newell F, Waddell N, Wood S, Mead RS, Xu Q, Wu J, Pinese M, Cowley MJ, Jones MD, Nagrial AM, Chin VT, Chantrill LA, Mawson A, Chou A, Scarlett CJ, Pinho AV, Rooman I, Giry-Laterriere M, Samra JS, Kench JG, Merrett ND, Toon CW, Epari K, Nguyen NQ, Barbour A, Zeps N, Jamieson NB, McKay CJ, Carter CR, Dickson EJ, Graham JS, Duthie F, Oien K, Hair J, Morton JP, Sansom OJ, Grützmann R, Hruban RH, Maitra A, Iacobuzio-Donahue CA, Schulick RD, Wolfgang CL, Morgan RA, Lawlor RT, Rusev B, Corbo V, Salvia R, Cataldo I, Tortora G, Tempero M, Australian Pancreatic Cancer Genome Initiative, Hofmann O, Eshleman JR, Pilarsky C, Scarpa A, Musgrove EA, Gill AJ, Pearson JP, Grimmond SM, Waddell N and Biankin AV. Hypermutation in pancreatic cancer. Gastroenterology. in press.
  4. Luchini C, Capelli P and Scarpa A. Pancreatic ductal adenocarcinoma and its variants. Surg Pathol Clinics. in press.
  5. Scarpa A, Corbo V, Barbi S, Cataldo I and Fassan M. Molecular Biology of Neuroendocrine Tumors. In: Book, ed.: Springer-Verlag; in press.

Sottoposti per la pubblicazione

  1. Scarpa A, Chang D, Nones K, Corbo V, Patch A, Bailey P, Lawlor RT, Johns A, Miller D, Mafficini A, Rusev B, Scardoni M, Antonello D, Barbi B, Sikora K, Cingarlini S, Vicentini C, Simpson S, Quinn M, Bruxner T, Christ A, Harliwong I, Idrisoglu S, McLean S, Nourse C, Nourbakhsh E, Wilson P, Anderson M, Fink L, Newell F, Waddell N, Holmes O, Kazakoff S, Leonard C, Wood S, Xu Q, Nagaraj S, Amato E, Dalai I, Bersani S, Cataldo I, Capelli P, Davì MV, Landoni L, Malpaga A, Miotto M, Whitehall V, Leggett B, Khanna KK, Harris J, Jones M, Humphris J, Chantrill L, Chin V, Nagrial A, Pajic M, Scarlett C, Pinho A, Rooman I, Toon C, Wu J, Pinese M, Cowley M, Barbour A, Mawson A, Humphrey E, Colvin E, Chou A, Lovell J, Jamieson N, Duthie F, Gingras MC, Fisher W, Dagg R, Lau L, Lee M, Pickett H, Reddel R, Samr J, Kench J, Merrett N, Epari K, Nguyen N, Zeps N, Falconi M, Simbolo M, Butturini G, Van Buren II G, Partelli S, Fassan M, Gill A, Wheeler D, Gibbs R, Musgrove E, Bassi C, Tortora G, Pederzoli P, Pearson J, Waddell N, Biankin A and Grimmond S. Novel mutational mechanisms and drivers in Pancreatic Neuroendocrine Tumours. Nature. Sottoposto
  2. Andrianello S, Marchegiani G, Malleo G, Rusev BR, Scarpa A, Bonamini D, Maggino L, Bassi C and Salvia R. Over 700 Whipples for malignancies of the pancreaticobiliary epithelium show that distal bile duct cancers are associated with poor surgical and survival outcomes. submitted.
  3. Chattaragada MS, Cappello P, Riganti C, Sassoe M, Principe M, Santamorena MM, Allavena P, Scarpa A and Novelli F. FAM49B, a novel mitochondria function and integrity regulator that suppresses tumor metastasis. submitted.
  4. Coinu A, Scarpa A, Petrelli F, Silvestris N, Azzariti A, Numico G, Brunetti AE, Vicentini C, Nardulli P and Barni S. Role of microRNA in exocrine pancreatic carcinoma. submitted.
  5. Crippa S, Partelli S, Bassi C, Berardi R, Capelli P, Scarpa A, Zamboni G and Falconi M. Neuroendocrine carcinomas of the pancreas (WHO G3): clinico-pathological characteristics, treatment considerations and long-term outcomes submitted.
  6. Gohil SH, Paredes-Moscosso SR, Harrasser M, Sorio C, Scarpa A, Davidoff AM, Nathwani AC and Della Peruta M. A ROR1 Bi-specific T-cell Engager provides effective targeting and cytotoxicity of a range of solid tumours. Oncoimmunology. submitted.
  7. Gomez-Rubio P, Rosatto V, Marquez M, Bosetti C, Molina E, Rava M, Michalski C, Farré A, Molero X, Löhr M, Ilzarbe L, Perea J, Greenhalf W, O’Rorke M, Tardón A, Gress T, Barberà V, Crnogorac-Jurcevic T, Muñoz-Bellvís L, Domínguez-Muñoz E, Balcells J, Costello E, Guillén-Ponce C, Huang J, Iglesias M, Kleeff J, Kong B, Mora J, Murray L, O’Driscoll D, Peláez P, Poves I, Lawlor RT, Carrato A, Hidalgo M, Scarpa A, Sharp L, Real FX, La Vecchia C, Malats N and on behalf of the PanGenEU Study Investigators. Multimorbidity patterns associate with pancreatic cancer risk

. submitted.

  1. Humphris JL, Pinese M, Patch AM, Johns AL, Nones K, Bailey P, McKay S, Cowley M, Nones K, Upstill-Goddard R, Chang DK, Bailey P, Miller D, Pajic M, Kassahn K, Wu J, Jones M, Nagrial A, Chin V, Humphrey E, Chantrill L, Colvin E, Wright D, Martin S, Quek K, Quinn M, Bruxner T, Christ A, Harliwong I, Idrisoglu S, Manning S, Nourse C, Nourbakhsh E, Wani S, Stone A, Wilson P, Anderson M, Fink L, Holmes O, Kazakoff S, Leonard C, Newell F, Taylor D, Waddell N, Wood S, Xu C, Mawson A, Chou A, Scarlett C, Pinho A, Rooman I, Samra J, Kench J, Lovell J, Merrett N, Toon C, Epari K, Nguyen N, Barbour A, Zeps N, Jamieson N, Dreyer S, Graham J, Duthie F, Oien K, McKay C, Grützmann R, Hruban R, Maitra A, Iacobuzio-Donahue C, Wolfgang C, Lawlor RT, Cantù C, Mafficini A, Rusev B, Malleo G, Marchegiani G, Salvia R, Tortora G, Mukhopadhyay D, Petersen G, Tempero M, Australian Pancreatic Cancer Genome Initiative, Hofmann O, Eshleman JR, Pilarsky C, Scarpa A, Musgrove EA, Gill AJ, Pearson JP, Grimmond SM, Waddell N and Biankin AV. Cancer drivers in the germline: are we missing a piece of the puzzle? NEJM. submitted.
  2. Jalla S, Groves C, Chesebrough J, Li Y, Gao J, Strout P, Baffa R, Dalai I, Sorio C, Scarpa A, Hurt E and Hollingsworth R. Pancreatic cancer: prevalence of cancer stem cells is related to tumor grade and resistance to therapy. bjc. submitted.
  3. Jusakul A, Cutcutache I, Lim JQ, Yong CH, Huang MN, Padmanabhan N, Kongpetch S, Choo SP, Myint SS, Lim WK, Ng CCY, Rajasegaran V, Ng AWT, Blöcker C, McPherson JR, Tiong ALS, Hui LT, Ong CK, Ng LM, Thangaraju S, Lie S, Nagarajan S, Liang MLJ, Tan J, Lai J, Luo D, Dima S, Duda D, Khuntikeo N, Bhudhisawasdi V, Yongvanit P, Wongkham S, Chow PKH, Chung A, Ooi LL, Lim KH, Park YN, Luiz A, Vettore AL, Scarpa S, Broet P, Popescu I, Pairojkul C, Shibata T, Rozen SG, Teh BT and Tan P. Whole Genomes Reveal Trans-Ethnic Mutational and Epigenetic Landscapes of Cholangiocarcinoma. Submitted.
  4. Kidd M, Knuth A, Meyer T, Scarpa A and Modlin I. Role of molecular biology in the detection and treatment of neuroendocrine liver metastases. submitted.
  5. Lawlor RT and Scarpa A. Models of collaboration and experiences between bio-industry and academic biobanks IARC; submitted(in press).
  6. Maria Elisa Perico1§ SG, Matteo Brunelli2, Rita. T. Lawlor2,3, Guido Martignoni2*, Giulio Fracasso1, Tiziana Cestari1, Hassan Naim4, Marco Colombatti1 and Dunia Ramarli5. Prostate-Specific Membrane Antigen (PSMA) assembles a macromolecular complex regulating growth and survival of prostate cancer cells “in vitro” and correlating with progression “in vivo”. submitted.
  1. Racanicchi L, Llampasona V, Nano R, Melzi R, Mercalli A, Pellegrini S, Sordi V, Doglioni D, Scarpa S and Piemonti L. Endocrine tumours as models for discovery of insulin regulators: insulinoma associated miR-204/211 correlate with the endocrine phenotype in normal pancreatic islets. submitted.
  2. Rogon Z, Bauer A, Giese T, Busch H, Szabowski A, Scarpa A, Zawatzky R, Soyka E, Magios N, Heller A, Hoheisel J, Werner J, Eils R and Giese N. Tumor cell dichotomy and the induction of 1 double-paracrine antiviral loop drive pancreatic tumor-stroma crosstalk. submitted.
  3. Simbolo M, Mafficini A, Sikora KO, Fassan M, Barbi S, Corbo V, Mastracci L, Rusev B, Grillo F, Vicentini C, Ferrara R, Pilotto S, Davini F, Pelosi G, Lawlor RT, Chilosi M, Tortora G, Bria E, Fontanini G, Volante M and Scarpa A. Lung neuroendocrine tumours: deep sequencing of the four WHO histotypes reveals chromatin remodeling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D. submitted.
  4. Vallath S, Reader CS, Steele CW, Barry ST, Haider S, Brentnall A, Desai A, Jamieson NB, Chang DK, Bailey P, Scarpa A, Lawlor R, Chelala C, Hart IR, Keyse SM, Biankin A, Morton JP, Evans JTR, Sansom OW, Kocher HM and Marshall JF. In vivo targeting of integrin αvβ6 with antibody 264RAD improves survival from pancreatic cancer Gut. submitted.